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News BioLegend: Leaf To Ultra-Leaf Antibody Transition

Marzo 2018

Currently, BioLegend offers a number of antibody formats suitable for use in both in vitroand in vivo assays. In an effort to continue to improve our high quality standards, over the next year and a half we will be discontinuing all of our LEAF™ purified antibodies and transitioning them to our Ultra-LEAF™ format. The Ultra-LEAF™ antibodies will remain azide-free and will be available in a wider range of sizes as described in the box below.

 

 

 Ultra-LEAF™ Purified anti-human CD95 (FAS) Antibody 

 

 

 

 

Recombinant FASL (Cat. No. 589402) induces cytotoxic effect in Jurkat human T cell leukemia cells in a dose dependent manner (grey circles). Anti-human - CD95 monoclonal antibody (Cat. No. 684401, clone A16086F, purple squares) blocks the cytotoxic effect induced by recombinant human FASL (60 ng/ml).
The ND50 = 0.01 - 0.05 μg/ml.

Ultra-LEAF™ Purified anti-human BMP9 (GDF2) Antibody

Recombinant human BMP9 (Cat. No. 553102) induces alkaline phosphatase in ATDC5 mouse chondrogenic cell line in a dose dependent manner (black circles). Anti-human BMP9 monoclonal antibody (Cat. No. 611703, clone A16035H, purple circles) neutralizes the production of alkaline phosphatase in ATDC5 cells induced by BMP9 (2 ng/mL).
The ND50 = 0.05 - 0.25 μg/mL.

    New Ultra-LEAF™ Antibodies                      New GoInVivo™ Antibodies

Specifity

Clone

 

Specifity

Clone

Anti-human BMP9 (GDF2)

A16035H

 

Anti-human/mouse/rat CD278 (ICOS)

C398.4A

 

Anti-human CD13

WM15

 

Anti-mouse IFN-γ

XMG1.2

Anti-human CD95 (FAS)

A16086F

 

Armenian Hamster IgG Isotype control

HTK888

Anti-mouse CD184 (CXCR4)

QA16A08

 

 

 

Anti-mouse CD274
(B7-H1, PD-L1)

MIH6

 

 

 

Anti-mouse CX3CR1

QA16A03

 

 

 

Anti-HMGB1

3E8

 

 

 

For further information please contact biolegend@campoverde-group.com

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